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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIST1H3A
All Species:
50.91
Human Site:
Y100
Identified Species:
93.33
UniProt:
P68431
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P68431
NP_003520.1
136
15404
Y100
L
Q
E
A
C
E
A
Y
L
V
G
L
F
E
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001082339
136
15430
Y100
L
Q
E
A
C
E
S
Y
L
V
G
L
F
E
D
Dog
Lupus familis
XP_537880
259
28976
Y100
L
Q
E
A
C
E
A
Y
L
V
G
L
F
E
D
Cat
Felis silvestris
Mouse
Mus musculus
NP_038576
136
15370
Y100
L
Q
E
A
S
E
A
Y
L
V
G
L
F
E
D
Rat
Rattus norvegicus
P84245
136
15309
Y100
L
Q
E
A
S
E
A
Y
L
V
G
L
F
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508660
182
20674
Y146
L
Q
E
A
S
E
A
Y
L
V
G
L
F
E
D
Chicken
Gallus gallus
Frog
Xenopus laevis
P02302
136
15469
Y100
L
Q
E
A
S
E
A
Y
L
V
A
L
F
E
D
Zebra Danio
Brachydanio rerio
XP_002666952
147
16698
Y111
L
Q
E
A
S
E
A
Y
L
V
G
L
F
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02299
136
15370
Y100
L
Q
E
A
S
E
A
Y
L
V
G
L
F
E
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P08898
136
15357
Y100
L
Q
E
A
C
E
A
Y
L
V
G
L
F
E
D
Sea Urchin
Strong. purpuratus
P06352
136
15483
Y100
L
Q
E
A
S
E
A
Y
L
V
R
L
F
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P59226
136
15249
Y100
L
Q
E
A
A
E
A
Y
L
V
G
L
F
E
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P07041
136
15373
Y100
L
Q
E
S
V
E
S
Y
L
V
S
L
F
E
D
Conservation
Percent
Protein Identity:
100
N.A.
98.5
52.5
N.A.
99.2
96.3
N.A.
74.1
N.A.
95.5
91.8
N.A.
99.2
N.A.
97.7
97.7
Protein Similarity:
100
N.A.
99.2
52.5
N.A.
99.2
98.5
N.A.
74.1
N.A.
96.3
91.8
N.A.
99.2
N.A.
99.2
98.5
P-Site Identity:
100
N.A.
93.3
100
N.A.
93.3
93.3
N.A.
93.3
N.A.
86.6
93.3
N.A.
93.3
N.A.
100
86.6
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
93.3
N.A.
93.3
N.A.
86.6
93.3
N.A.
93.3
N.A.
100
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
97
N.A.
89.7
Protein Similarity:
N.A.
N.A.
N.A.
98.5
N.A.
95.5
P-Site Identity:
N.A.
N.A.
N.A.
93.3
N.A.
73.3
P-Site Similarity:
N.A.
N.A.
N.A.
93.3
N.A.
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
93
8
0
85
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
31
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% D
% Glu:
0
0
100
0
0
100
0
0
0
0
0
0
0
100
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
77
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
100
0
0
0
0
0
0
0
100
0
0
100
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
0
0
8
54
0
16
0
0
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
8
0
0
0
0
100
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _